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Functions of L-theanine

by BiotechAusway 27 May 2025

I. Neuromodulation and Mood Regulation

  • Stress Relief and Relaxation: Stimulates alpha brain wave production, increases dopamine and serotonin levels, reduces cortisol (stress hormone) concentrations, and alleviates anxiety.

  • Improved Sleep Quality: Enhances gamma-aminobutyric acid (GABA) release, shortens sleep latency, and deepens sleep.

  • Reduced Physical Fatigue: Modulates excitability in the central nervous system, alleviating fatigue caused by overexertion.

  • Neuroprotective Effects: Inhibits neuronal cell death induced by cerebral ischemia and delays neurodegenerative disorders like Alzheimer’s disease.

II. Cognitive Enhancement

  • Memory and Attention Improvement: Balances glutamate and GABA activity, enhancing brain cell vitality and information processing.

  • Synergy with Caffeine: Works synergistically with caffeine to boost alertness, reaction speed, and executive function while reducing caffeine-induced jitteriness.

III. Cardiovascular Health Support

  • Blood Pressure and Circulation Regulation: Inhibits angiotensin-converting enzyme (ACE) activity, promotes nitric oxide synthesis, dilates blood vessels, and improves cerebral/systemic blood flow.

  • Reduced Cardiovascular Disease Risk: Mitigates arteriosclerosis and thrombosis, supporting cardiovascular health.

IV. Immune System Enhancement

  • Immune Cell Activation: Boosts activity of T cells and natural killer (NK) cells, strengthening antiviral and anti-infective capabilities.

  • Disease Prevention: Long-term intake may lower risks of respiratory infections like influenza.

V. Antioxidant and Anti-inflammatory Effects

  • Free Radical Scavenging: Reduces oxidative stress damage to cells and DNA, delaying skin and organ aging.

  • Inflammation Suppression: Regulates immune responses by reducing inflammatory mediators and inflammatory cell infiltration.

VI. Additional Physiological Functions

  • Anti-fatigue and Anti-aging: Reduces oxidative damage and regulates metabolism to maintain vitality.

  • Anti-tumor Potential: Emerging studies suggest it may aid chemotherapy responses in cancer treatment.

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